The short answer

Red light therapy may help knee pain a little, mainly in knee osteoarthritis. A 2024 review of 13 trials (673 adults) found less pain after about 8 weeks, and a 2025 umbrella review rated better knee function as moderate-certainty evidence.

Use it alongside exercise, not instead of it. At home, REX MINI (AED 599) covers one knee at a time and REX ULTRA (AED 2,499) covers larger areas.

Trials reviewed13

Knee osteoarthritis, 2024 review

Adults studied673

Across those 13 trials

Measured at8 weeks

Of regular sessions

Knee functionModerate

Certainty, 2025 umbrella review

The evidence

Does red light therapy help knee pain?

Sometimes, and modestly. The clearest research is in knee osteoarthritis, the most common kind of knee arthritis. Here is what the newest reviews found.

2024 review Fan et al., Aging Clinical and Experimental Research

13 trials, 673 adults with knee osteoarthritis

Less pain than sham light after about 8 weeks. No clear change in stiffness or function.

Low certainty
2025 umbrella review Son et al., Systematic Reviews

15 meta-analyses, 204 trials, over 9,000 people, 35 health outcomes

Better function (less disability) in knee osteoarthritis: one of only 5 outcomes rated moderate certainty.

Moderate certainty
UK guideline, 2022 NICE guideline NG226

Osteoarthritis care

Therapeutic exercise and, where relevant, weight management come first. Laser therapy is not recommended, citing insufficient evidence.

Guideline
Moderate certainty: the real effect is probably close to what the studies found.
Low certainty: it could be quite different once bigger, better trials report.

The two reviews don't fully agree on function, which is common when trials are small and use different devices and doses. Read the results as promising, not proven.

Know the limits

What red light therapy can't do for your knees

It can't stand in for the basics, and the research has clear limits.

01It doesn't replace exercise

NICE puts therapeutic exercise at the core of osteoarthritis care. Its 2022 guideline doesn't recommend laser therapy, citing insufficient evidence. Reviews published since are more positive, but still not strong.

02It isn't shown to repair cartilage

The trials measured pain, stiffness and function, not the joint itself.

03Sports knee pain is a different question

The evidence is for osteoarthritis. It says little about runner's knee, tendon pain or a padel twist, so get those checked first.

04Home devices weren't what was tested

Trials used specific devices at doses set by researchers, so their results don't transfer automatically to any home device, REX included.

Red vs near-infrared

Red or near-infrared: which light reaches the knee?

Near-infrared. It travels deeper into tissue than visible red light, which matters for a joint as large as the knee. The 2024 review compared three wavelength groups:

Wavelength groupEvidence for knee painIn REX devices?
904 to 905 nmRanked best, low certaintyNo
785 to 850 nmWeaker, very low certaintyPanels: 810, 830 and 850 nm. REX MINI: 850 nm
Multi-wavelength devicesWeaker, very low certaintyREX panels use 9 wavelengths
REX ULTRA, PRO, CORE and PRESTIGE
480 nm 630 nm 650 nm 660 nm 670 nm 810 nm 830 nm 850 nm 1060 nm
REX MINI
660 nm 850 nm
Dose matters as much as wavelength

No REX device uses 904 to 905 nm, and a wavelength list alone can't predict a study's result: power, distance and session time decide how much light reaches the knee. Our guide to irradiance, distance and dose shows how to compare devices.

Your home routine

How to use red light therapy on your knee at home

Bare skin, close to the joint, on a steady routine for about 8 weeks, alongside your exercises.

How oftenTwice a day
Panel session15 to 25 min
SkinBare and dry
EyesGoggles on
Give it8 weeks
Man seated on a mat holding a REX MINI red light device against the front of his knee
REX MINI held close to the knee. Light the front, then the inner and outer sides.
  1. 01
    Rule out an injury firstIf the knee is swollen, hot, locking or giving way, see a doctor or physiotherapist before anything else.
  2. 02
    Expose the kneeFabric blocks much of the light, so use it on clean, dry, bare skin.
  3. 03
    Cover the whole jointLight the front of the knee, then the inner and outer sides. With a panel, sit so both knees face it.
  4. 04
    Keep to the routineREX panels: twice a day, 15 to 25 minutes a session. REX MINI: hold it close to the skin and move it across the front and sides of the knee.
  5. 05
    Protect your eyesNever look into the LEDs, and wear the goggles that come with every REX panel.
  6. 06
    Stay consistent for 8 weeksThat is when the trials measured results. Once a week, note your pain (0 to 10) and how stairs and walking feel.
  7. 07
    Keep movingRed light sits alongside the exercises your physiotherapist sets, never in place of them.
Choose your device

Which REX is right for knee pain?

REX MINI for one knee at home or on the go, REX ULTRA for larger areas, REX PRO for legs and back together.

REX MINI handheld red light therapy device held in one hand
Handheld REX MINI

24 LEDs, 660 and 850 nm

One knee at a time, after padel, a run or travel.

REX ULTRA red light therapy panel on its tilting desk stand
1 ft panel REX ULTRA

72 LEDs, 9 wavelengths, tilting desk stand

Larger areas at home.

REX PRO 3 ft red light therapy panel on its wheeled floor stand
3 ft panel REX PRO

288 LEDs, 9 wavelengths, wheeled floor stand

Knees, thighs and lower back in one session.

AED 7,999View REX PRO

Delivery is free across the UAE, and our team installs panels for you. Not sure which fits? Take the product quiz or book a 15-minute demo on WhatsApp: +971 58 586 5195.

Safety first

When should you see a doctor about knee pain?

Before you start, if the pain followed an injury or the knee looks or feels wrong. See a doctor or physiotherapist first if:

  • !the pain started with a fall, a twist or a pop, or the knee swelled quickly
  • !the knee is hot, red or swollen, or you have a fever
  • !it locks, catches or gives way
  • !you can't put weight on it, or the pain wakes you at night

Check with your doctor before using any light device if you are pregnant, have a light-sensitivity condition, take medicine that makes your skin sensitive to light, or are unsure whether it suits you.

FAQ

Frequently asked questions

How long does red light therapy take to work on knees?

The trials in the 2024 review measured results at about 8 weeks, so keep a steady routine at least that long before you judge it. Results vary from person to person.

Can red light therapy replace physiotherapy for knee pain?

No. Therapeutic exercise is the core of knee osteoarthritis care in the 2022 NICE guideline. Red light can sit alongside it, not replace it.

Does red light therapy help runner's knee or padel knee pain?

The evidence is thinner. The reviews above studied osteoarthritis, not sports injuries, so get a diagnosis first. Playing padel? Our guide to red light therapy for neck pain and padel recovery covers your routine.

Which wavelength is best for knee pain?

No wavelength has strong evidence yet. In the 2024 review, 904 to 905 nm ranked best for pain, at low certainty. Near-infrared (810 to 850 nm) reaches deeper than red, and dose matters as much as wavelength.

Can I use red light therapy on my knee every day?

The REX panel routine is twice a day, 15 to 25 minutes a session. That is our product guidance, not a medical prescription, so follow your model's instructions and your doctor's advice.

Does red light therapy repair knee cartilage?

The studies above didn't measure cartilage, so there is no evidence here that it repairs a worn knee. They measured pain, stiffness and function.

The bottom line

A reasonable add-on for knee osteoarthritis, with realistic expectations

Modest benefits, low to moderate certainty, about 8 weeks of consistency, and exercise as the foundation. Start with REX MINI for one knee, or compare the full REX range.

Shop REX MINI Compare REX WhatsApp demo

Sources

  1. Fan T, et al. Aging Clinical and Experimental Research, 2024; 36: 203. Systematic review and network meta-analysis of 13 trials in knee osteoarthritis. doi.org/10.1007/s40520-024-02853-0
  2. Son Y, et al. Systematic Reviews, 2025. Umbrella review of photobiomodulation trials across 35 health outcomes. doi.org/10.1186/s13643-025-02902-3
  3. NICE. Osteoarthritis in over 16s: diagnosis and management, guideline NG226, 2022. nice.org.uk/guidance/ng226
Red light therapy devices don't replace medical advice, diagnosis or physiotherapy.